Four colleagues and I attended the Controlled Release Society’s (CRS) annual meeting in Quebec City July 15-18. Quebec City was a delightful venue with the Old City filled each day and night with tourists for the annual music festival, outdoor Cirque du Soleil presentations, and summer Images presentations, coupled with celebration of the 400th anniversary of the founding of Quebec.
CRS was a good meeting and I saw a number of posters and several presentations related to melt extrusion of polymers for drug delivery formulations. I attended the following three technology workshops:
- Gattefossé: “Lipid Excipients: Born To Be Extruded”
- Catalent: “Recent Advances in Oral Granules and Bi-Layer Tablet Technologies, Solubility Enhancement Solutions, and Oral Disintegrating Tablet Applications”
- Grünenthal: “Innovative Tamper Resistant Formulation (TRF) Technology – Protecting Intended Drug Action”
I found these workshops to be very informative in highlighting features that melt extrusion can provide in drug delivery systems.
A “Soap Box” (5 minute) presentation from Harvard University involved ocular delivery of a drug to the eye by way of a drug-polymer film encapsulated in the periphery of a hydrogel-based contact lens. I thought this was an intriguing ocular delivery concept.
A podium presentation by a researcher from the University of Bath used ethylene vinyl acetate copolymers (EVA) in electrospun fibers to release tetracycline.
A poster was presented on behalf of the International Pharmaceutical Excipients Council of the Americas on their New Excipient Safety Evaluation Procedure, which is a joint effort of excipient producers and users to develop a framework for data creation and review that will encourage and enable the evaluation of new, value-adding excipients. Hopefully, this will help innovators overcome this hurdle to consideration of new excipients.
Thanks to those of you who attended our dinner presentation. We enjoyed meeting each of you and look forward to working with you in the future. For all of you we saw over the course of the entire meeting, we look forward to seeing you again!
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